Good (n = 9) | Moderate (n = 17) | No response (n = 9) | |||||||
---|---|---|---|---|---|---|---|---|---|
Plasma levels | Before treatment | After treatment | p Value | Before treatment | After ?treatment | p Value | Before treatment | After treatment | p Value |
Data are shown as mean (SD) before and after 14 weeks after treatment. p Values show the differences between baseline and the follow up in every group (Wilcoxon matched pairs test). | |||||||||
CRP | 33 (24.8) | 2.2 (1.8) | <0.01 | 31.6 (25.7) | 15.2 (26.2) | <0.001 | 57.2 (48.6) | 45.6 (44.4) | 0.160 |
C3b/c | 33.3 (11.8) | 22.8 (6.9) | 0.054 | 24.6 (10.9) | 17.5 (6.4) | <0.01 | 27.4 (9.1) | 34.1 (25.2) | 0.547 |
C4b/c | 60.1 (49.8) | 58 (45.6) | 0.91 | 37.4 (31.8) | 22.9 (13.4) | 0.120 | 39 (25.5) | 23.4 (6.6) | 0.431 |
CRP-C3d | 406 (417.5) | 62 (65.2) | <0.05 | 434 (502.4) | 145 (276.6) | <0.001 | 1043 (1249) | 535 (507) | 0.250 |
CRP-C4d | 632 (686.6) | 83 (142.6) | <0.05 | 370 (379.7) | 148 (334) | <0.01 | 1071 (1403) | 598 (806) | 0.312 |