Table 1

 Expression of cryopyrin and ASC in RA synovial lining and sublining

Gene productRA synovial lining (REU)*RA synovial sublining (REU)p Value
*Data are expressed as mean (SEM) of GAPDH normalised REU from two microdissected regions each of seven (cryopyrin and ASC) or four (pyrin) RA synovial cryosections. There was no significant difference in gene expression between lining and sublining regions for any transcript.
Cryopyrin2.50 (0.74)4.44 (1.70)0.56
ASC3.97 (0.60)4.28 (0.73)0.99
Pyrin0.68 (0.23)0.83 (0.27)0.70