Table 1

Anti-α-fodrin antibodies in Sjögren’s syndrome and other autoimmune diseases: analysis of published reports

Anti-α-fodrin method	pSS	sSS		SLE	RA	MS	Controls
Anti-α-fodrin method	pSS	SLE	RA	SLE	RA	MS	Controls
Results are expressed as percentage.
pSS, primary Sjögren’s syndrome; sSS, secondary Sjögren’s syndrome; SLE, systemic lupus erythematosus; RA, rheumatoid arthritis; MS, multiple sclerosis.
*pSS with neurological manifestations; †pSS without neurological manifestations,
Witte et al⁸
Number	85	15	7	50	12		160
ELISA						ND
IgA	64	47	86	2	17		<1
IgG	55	40	43	2	42		2

Witte et al¹
Number	136						207
ELISA		ND	ND	ND	ND	ND
IgA	78.7						2.9
IgG	66.2						3.4

De Seze et al^9,¹⁰
ELISA (n)	84	ND	ND	38	ND	60	160
IgA or Ig G	64.5*/73.6†			15.8		13.3	6.3

Zandbelt et al⁴
ELISA (n)	21	4	ND	6	12	ND	28
IgA	43	75		0	8.3		0
IgG	48	75		0	50		0

Ruffati et al⁵
ELISA (n)	80	ND	ND	50	30	ND	60
IgA	32.5			32	46.7		1.7
IgG	21.3			26	13.3		8.3

Haneji et al⁶
Number	43	8	ND	21	14	ND	15
Immnublotting	95.4	87.5		0	0		0

Watanabe et al78]
Number	9	15	ND	44	ND	ND	ND
Immunoblotting	78	60		7

Nordmark et al³
Number	56	14	ND	ND	53	ND	ND
Immunoprecipitation	29	21			47

Current report
ELISA (normal <15 U/l) (n)	107	ND	ND	32	43	ND	48
IgA	17.7			25	23.3		12.5
IgG	5.6			21.8	2.32		0
Home made (normal (0.280) (n)	52			ND	ND		29
IgA, IgG, IgM (%)	7.6						0