Mean 28 joint disease activity score (DAS28) and reduction in DAS28
| Groups according to resistance markers | Change in DAS28 | Mean DAS28 at start of treatment | Mean DAS28 at time of blood sampling | p Value v fMRP−/RFC+ | |
|---|---|---|---|---|---|
| Values are mean (SD). | |||||
| fMRP, functional multidrug resistance proteins; RFC, reduced folate carrier. | |||||
| fMRP−/RFC+ (n = 70) | 0.71 (1.27) | 3.08 (1.02) | 2.37 (1.00) | ||
| fMRP−/RFC− (n = 32) | 1.23 (1.44) | 3.22 (1.30) | 1.99 (0.93) | 0.035 | |
| fMRP+/RFC+ (n = 33) | 1.32 (1.36) | 3.38 (1.10) | 2.05 (1.14) | 0.014 | |
| fMRP+/RFC− (n = 28) | 1.09 (1.29) | 3.39 (0.95) | 2.30 (0.98) | NS | |