The odds ratios of site sharing (symptomatic osteoarthritis) in patients with familial osteoarthritis at multiple sites
| Osteoarthritis site | Sibling OA+ | Sibling OA− | Crude OR (95%CI) | Adjusted OR (95%CI) | |
|---|---|---|---|---|---|
| Values are expressed as crude and adjusted odds ratios (95% confidence interval) for age, sex, and body mass index in the 191 sibling pairs included in the GARP study. | |||||
| CI, confidence interval; CMC1, first carpometacarpal joint; DIP, distal interphalangeal joint; OA+, with osteoarthritis; OA−, without osteoarthritis; OR, odds ratio; PIP, proximal interphalangeal joint. | |||||
| Hand | Proband OA+ | 109 | 39 | 3.5 (1.7 to 7.1) | 4.4 (2.0 to 9.5) |
| Proband OA− | 19 | 24 | |||
| DIP | Proband OA+ | 45 | 48 | 2.2 (1.2 to 4.0) | 2.3 (1.2 to 4.4) |
| Proband OA− | 29 | 69 | |||
| PIP | Proband OA+ | 35 | 46 | 1.9 (1.1 to 3.6) | 1.8 (1.0 to 3.4) |
| Proband OA− | 31 | 79 | |||
| CMC1 | Proband OA+ | 21 | 36 | 2.4 (1.2 to 4.8) | 2.6 (1.2 to 5.4) |
| Proband OA− | 26 | 108 | |||
| Spine | Proband OA+ | 125 | 20 | 2.2 (1.0 to 5.0) | 2.2 (1.0 to 5.1) |
| Proband OA− | 34 | 12 | |||
| Hip | Proband OA+ | 23 | 26 | 5.1 (2.5 to 10.6) | 3.9 (1.8 to 8.4) |
| Proband OA− | 21 | 121 | |||
| Knee | Proband OA+ | 23 | 47 | 1.1 (0.6 to 2.1) | 1.0 (0.5 to 2.0) |
| Proband OA− | 37 | 84 | |||