Characteristics of probands and siblings with familial osteoarthritis at multiple sites of the 191 sibling pairs included in the GARP study
| Variable | Probands | Siblings |
|---|---|---|
| *p<0.05, probands v siblings. | ||
| AUSCAN, Australian/Canadian osteoarthritis hand index; BMI, body mass index; WOMAC, Western Ontario and McMaster Universities osteoarthritis index. | ||
| Women (n (%)) | 162 (85) | 150 (79) |
| Age (years) (mean (range)) | 59.9 (46 to 76) | 60.6 (43 to 79) |
| BMI (kg/m2) (median (range)) | 26.9 (20 to 46) | 26.2 (19 to 46) |
| Structural abnormalities at multiple sites (n (%)) | 191 (100) | 191 (100) |
| Symptomatic osteoarthritis at multiple sites (n (%)) | 178 (93) | 166 (87) |
| Pain or stiffness at multiple sites (n (%)) | 185 (97) | 187 (98) |
| WOMAC 0–100 (median (range)) | 27.3 (0 to 95) | 18.7 (0 to 88)* |
| AUSCAN 0–60 (median (range)) | 19.0 (0 to 59) | 15.0 (0 to 54)* |