Classification and regression tree and regression analyses for exploratory definitions of ultrasound detected inflammation
| Alternative definitions of synovial disease | LR+ | Logistic regression (adjusted by country) | ||
|---|---|---|---|---|
| Selected parameter | OR (95% CI) | |||
| LR+, positive likelihood ratio. | ||||
| *Maximum radiographic grade ⩾3 refers to the Kellgren and Lawrence radiological grade in any of the three knee compartments (medial and lateral femorotibial and patellofemoral compartments of studied knee); †knee joint effusion graded “moderate” or “important” on clinical examination. | ||||
| A. Synovial thickness ⩾4 mm and diffuse or nodular appearance or effusion depth ⩾4 mm | 1.39 | Maximum radiographic grade* ⩾3 | 1.95 (1.36 to 2.81) | |
| Knee joint effusion on clinical examination† | 3.11 (2.03 to 4.77) | |||
| B. Synovial thickness ⩾2 mm and diffuse appearance or synovial thickness ⩾4 mm and nodular appearance | 1.57 | Maximum radiographic grade ⩾3 | 2.46 (1.65 to 3.68) | |
| Knee joint effusion on clinical examination | 1.96 (1.28 to 2.98) | |||
| C. Synovial thickness ⩾2 mm and diffuse appearance or synovial thickness ⩾4 mm and nodular appearance or effusion depth ⩾4 mm | 1.44 | Maximum radiographic grade ⩾3 | 2.12 (1.47 to 3.05) | |
| Knee joint effusion on clinical examination | 3.4 (2.18 to 5.26) | |||