TGFB1 haplotype | Controls (n = 194) | Patients (n = 134) | OR* (95% CI) | ||||
---|---|---|---|---|---|---|---|
n (%) | PF, n (%) | HF (%) | n (%) | PF, n (%) | HF (%) | ||
*Overall odds ratios for carriership of haplotypes 1–3. | |||||||
Haplotype 1: TGFB1+869T−TGFB1+915G; haplotype 2: TGFB1+869C−TGFB1+915G; haplotype 3: TGFB1+869C−TGFB1+915C. | |||||||
CI, confidence interval; HF, haplotype frequency; n, number of individuals; OR, odds ratio; PF, phenotype frequency. | |||||||
1.1 | 80 (41.2) | 174 (89.7) | 65.5 | 57 (42.5) | 116 (86.6) | 64.6 | 1.35 (0.69 to 2.66) |
1.2 | 76 (39.2) | 40 (29.9) | |||||
1.3 | 18 (9.3) | 19 (14.2) | |||||
2.2 | 12 (6.2) | 96 (49.5) | 27.8 | 10 (7.5) | 57 (42.5) | 25.0 | 1.32 (0.85 to 2.06) |
2.3 | 8 (4.1) | 7 (5.2) | |||||
3.3 | 0 | 26 (13.4) | 6.7 | 1 (0.7) | 27 (20.1) | 10.4 | 0.61 (0.34 to 1.11) |