Clinical characteristics of patients with ankylosing spondylitis (n = 113) in relation to carriage of the CD14-260T or the TLR4 896G allele
| Characteristics | TLR4 896G | CD14 260T | ||||||
|---|---|---|---|---|---|---|---|---|
| Carrier | Non-carrier | OR (95% CI) | p | Carrier | Non-carrier | OR (95% CI) | p | |
| AAU, acute anterior uveitis; PA, peripheral arthritis; familial, patients with at least one first degree family member with AS; +/−, present/not present; years to actual diagnosis, number of years between the first complaints and the actual diagnosis of AS. *Mann-Whitney test. | ||||||||
| Female/male | 1/6 | 12/85 | 1.18 (0.13 to 10.67) | 1.0 | 11/72 | 2/19 | 1.45(0.30 to 7.11) | 1.0 |
| PA (+/−) | 3/4 | 35/60 | 0.78 (0.16 to 3.68) | 1.0 | 33/48 | 5/16 | 0.46(0.15 to 1.36) | 0.15 |
| AAU(+/−) | 5/2 | 34/57 | 0.24 (0.04 to 1.30) | 0.11 | 31/48 | 8/11 | 1.13(0.41 to 3.11) | 0.82 |
| Familial(+/−) | 2/4 | 23/61 | 0.75 (0.13 to 4.40) | 0.67 | 21/51 | 4/14 | 0.69(0.20 to 2.36) | 0.56 |
| Age at first complaints, mean(SD) (range) | 23.83 (6.18) (18 to 32) | 25.64 (9.78) (9 to 55) | 0.57* | 25.17 (9.39) (9 to 51) | 25.89 (10.37) (16 to 55) | 0.63* | ||
| Years to actual diagnosis, mean (SD) (range) | 9.08 (11.43) (1 to 32) | 9.27 (8.83) (1 to 40) | 0.77* | 8.99 (8.79) (1 to 37) | 10.33 (9.74) (1 to 40) | 0.43* | ||