Characteristics of all patients
| Characteristic | All patients (n = 164) (⩾3 SS items) | SS (n = 108) (⩾4 SS items) | SS-like syndrome (n = 56) (3 SS items) |
|---|---|---|---|
| *SS, Sjögren’s syndrome; RF, rheumatoid factor; anti-CCP, anti-cyclic citrullinated peptide; PPV, positive predictive value; NPV, negative predictive value; CI, confidence interval. | |||
| Age (years), mean (range) | 56.3 (20.1–87.3) | 57.1 (24.9–87.3) | 54.6 (20.1–81.9) |
| Female/male ratio | 9.25/1 | 8/1 | 13/1 |
| Follow up | |||
| Years | 855.8 | 627.0 | 225.4 |
| Median | 3.65 | 4.30 | 2.75 |
| Range | 0–21.6 | 0–21.6 | 0.2–15.9 |
| Anti-SSA/Ro, No (%) | 94 (57) | 77 (71) | 17 (30) |
| Anti-SSB/La, No (%) | 71 (43) | 62 (57) | 9 (16) |
| RF, No (%) | 67 (41) | 52 (48) | 15 (27) |
| Anti-CCP, No (%) | 5 (3) | 3 (3) | 2 (4) |
| Anti-CCP, No (%) | |||
| Specificity (%) | 98.8 | 98.1 | 100 |
| Sensitivity (%) | 75 | 50 | 100 |
| PPV (%) | 60 | 50 | 100 |
| NPV (%) | 99.4 | 98.1 | 100 |
| RF | |||
| Specificity (%) | 60.6 | 52.8 | 75.9 |
| Sensitivity (%) | 100 | 100 | 100 |
| PPV (%) | 6.0 | 3.8 | 13.3 |
| NPV (%) | 100 | 100 | 100 |
| McNemar’s test (p value) | <0.0001 | <0.0001 | <0.0001 |
| κ Value (95% CI) | 0.058 (−0.013 to 0.129) | 0.021 (−0.044 to 0.086) | 0.184 (−0.041 to 0.410) |