Associations between autoantibodies and clinical symptoms
| Antibody | Associated symptom | OR | 95% CI for OR |
|---|---|---|---|
| OR, odds ratio; 95% CI, 95% confidence interval. | |||
| *Inverse associations (OR<1.0). | |||
| p Value ⩽0.001 | |||
| RNP-70k | Raynaud’s phenomenon past year | 19.5 | 4.4 to 86.2 |
| RNP-70k | Raynaud’ s phenomenon ever | 15.3 | 3.5 to 67.1 |
| Ribosomal P | Haemolytic anaemia past year | 8.6 | 2.5 to 28.8 |
| RNP-A | Raynaud’s phenomenon ever | 7.3 | 3.1 to 17.6 |
| RNP-A | Raynaud’s phenomenon past year | 7.0 | 3.1 to 15.8 |
| At least 2 RNP reactivities | Raynaud’s phenomenon past year | 5.6 | 2.4 to 12.7 |
| At least 2 RNP reactivities | Raynaud’s phenomenon ever | 5.0 | 2.1 to 11.6 |
| Ribosomal P | Alopecia past year | 4.4 | 1.7 to 11.2 |
| At least 2 RNP reactivities | Fever past year | 3.8 | 1.6 to 8.8 |
| At least 1 antibody of cluster 1 | Raynaud’s phenomenon past year | 3.6 | 2.0 to 6.7 |
| At least 1 antibody of cluster 2 | Xerostomia ever | 3.4 | 1.6 to 7.1 |
| RNP-A | Leucopenia past year | 3.2 | 1.5 to 6.5 |
| At least 1 antibody of cluster 1 | Raynaud’s phenomenon ever | 2.8 | 1.5 to 5.0 |
| p Value ⩽0.01 | |||
| SSB | Pericarditis past year | 7.1 | 1.9 to 26.7 |
| Ribosomal P | Haemolytic anaemia ever | 4.2 | 1.5 to 11.6 |
| SSB | Xerostomia ever | 4.0 | 1.6 to 10.0 |
| SSB | Xerostomia past year | 3.6 | 1.4 to 9.3 |
| RNP-A | Arthralgia past year | 3.4 | 1.4 to 8.6 |
| RNP-70k | Leucopenia past year | 3.4 | 1.4 to 8.0 |
| Ribosomal P | Leucopenia past year | 3.4 | 1.4 to 8.0 |
| At least 2 RNP reactivities | Leucopenia past year | 3.2 | 1.5 to 6.6 |
| At least 1 antibody of cluster 2 | Xerostomia past year | 3.2 | 1.5 to 6.8 |
| Ro52 or Ro60 | Xerostomia ever | 3.1 | 1.5 to 6.4 |
| Ro60 | Xerostomia ever | 3.1 | 1.5 to 6.4 |
| dsDNA | Cellular casts past year | 3.1 | 1.4 to 7.1 |
| At least 2 RNP reactivities | Arthritis past year | 3.1 | 1.4 to 6.6 |
| Ro52 or Ro60 | Xerostomia past year | 2.9 | 1.3 to 6.1 |
| At least 1 antibody of cluster 2 | Xerophthalmia ever | 2.7 | 1.3 to 5.8 |
| Ro60 | Xerostomia past year | 2.7 | 1.3 to 5.8 |
| At least 1 antibody of cluster 2 | Pericarditis ever | 2.5 | 1.2 to 5.2 |
| RNP-C | Raynaud’s phenomenon past year | 2.5 | 1.3 to 4.9 |
| At least 1 antibody of cluster 1 | Butterfly rash ever | 2.4 | 1.2 to 4.5 |
| Histones | Arthritis past year | 2.3 | 1.2 to 4.4 |
| RNP-70k | Fatigue ever | 1.2 | 1.1 to 1.3 |
| dsDNA | Photosensitivity ever* | 0.4 | 0.2 to 0.7 |
| RNP-A | Cellular casts ever* | 0.3 | 0.1 to 0.7 |
| RNP-C | Cellular casts ever* | 0.3 | 0.1 to 0.7 |