T cell subpopulations and activated T cells in peripheral blood in controls and in patients with active and inactive dermatomyositis
| Patients with aDM (n = 29) | Patients with iDM (n = 20) | Controls (n = 32) | p Values | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| aDM v control | iDM v control | aDM v iDM | ||||||||||
| Values are mean (SD). Significant p values in bold. | ||||||||||||
| The samples were measured by flow cytometry and lymphocytes were identified on the basis of their scatter properties. | ||||||||||||
| aDM, active dermatomyositis; iDM, inactive dermatomyositis. | ||||||||||||
| CD3+ cells (%) | 64.8 (11.4) | 71.8 (7.1) | 70.3 (7.2) | p<0.01 | NS | p<0.05 | ||||||
| CD4+ cells(%) | 48.3 (10.1) | 49.2 (10.9) | 45.2 (7.6) | NS | NS | NS | ||||||
| CD8+ cells (%) | 15.1 (7.1) | 20.9 (9.3) | 19.6 (5.9) | p<0.01 | NS | p<0.05 | ||||||
| CD19+ cells (%) | 16.8 (10.7) | 11.1 (4.3) | 11.7 (4.1) | p<0.01 | NS | p<0.05 | ||||||
| CD3+ and HLADR+ cells (%) | 6.4 (4.1) | 7.4 (5.7) | 3.0 (2.3) | p<0.01 | p<0.01 | NS | ||||||
| CD3+ and CD69+ cells (%) | 1.4 (0.9) | 1.3 (0.7) | 1.0 (0.8) | NS | NS | NS | ||||||