Autoantibody positivities in active and inactive polymyositis (aPM and iPM) and dermatomyositis (aDM and iDM)
| Active disease | Inactive disease | p Value | ||||
|---|---|---|---|---|---|---|
| Values are mean (SD) or n unless specified. Significant p values in bold. | ||||||
| ANF, antinuclear factor; CK, creatine kinase; ENA, extractable nuclear antigen; LDH, lactate dehydrogenase. | ||||||
| Dermatomyositis | ||||||
| n | 29 | 20 | ||||
| Age (years) | 46.5 (13.5) | 47.4 (13.6) | NS | |||
| Age range (years) | 13 to 70 | 24 to 73 | ||||
| Male/female | 11/18 | 5/15 | ||||
| CK (U/l) | 1371 (2254) | 74 (35) | p = 0.01 | |||
| LDH (U/l) | 764 (527) | 362 (84) | p<0.01 | |||
| Anti-ENA positivity | 4 | 2 | NS | |||
| Anti-Jo-1 positivity | 1 | 0 | NS | |||
| ANF HEp-2 positivity | 4 | 9 | NS | |||
| Polymyositis | ||||||
| n | 13 | 37 | ||||
| Age (years) | 43.1 (14.1) | 46.9 (13.6) | NS | |||
| Age range (years) | 20 to 69 | 18–69 | ||||
| Male/female | 5/8 | 8/29 | ||||
| CK | 1000 (1873) | 169 (235) | p = 0.01 | |||
| LDH | 1028 (1430) | 394 (143) | p = 0.01 | |||
| Anti-ENA positivity | 5 | 4 | p = 0.03 | |||
| Anti-Jo-1 positivity | 4 | 2 | p = 0.01 | |||
| ANF HEp-2 positivity | 3 | 4 | NS | |||