Comparison between the genotypes of the two polymorphisms and the ACR criteria
| ACR criteria (1–11) | PvuII | p Value* | XbaI | p Value* | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CC (n = 45) | TC (n = 132) | TT (n = 83) | GG (n = 21) | AG (n = 94) | AA (n = 145) | |||||||||||
| Values are n (%). | ||||||||||||||||
| *Calculated by χ2 with two degrees of freedom. | ||||||||||||||||
| 1. Malar rash | 27 (60.0) | 84 (63.6) | 38 (45.8) | 0.022 | 14 (66.7) | 60 (63.8) | 75 (51.7) | 0.12 | ||||||||
| 2. Discoid rash | 15 (33.3) | 42 (31.8) | 18 (21.7) | 0.21 | 8 (38.1) | 25 (26.6) | 42 (29.0) | 0.57 | ||||||||
| 3. Photosensitivity | 32 (71.1) | 89 (67.4) | 51 (61.4) | 0.49 | 17 (81.0) | 70 (74.5) | 85 (58.6) | 0.013 | ||||||||
| 4. Oral ulcer | 10 (22.2) | 24 (18.2) | 14 (16.9) | 0.75 | 4 (19.0) | 15 (16.0) | 29 (20.0) | 0.73 | ||||||||
| 5. Arthritis | 33 (73.3) | 97 (73.5) | 65 (78.3) | 0.70 | 12 (57.1) | 74 (78.7) | 109 (75.2) | 0.12 | ||||||||
| 6. Serositis | 19 (42.2) | 50 (37.9) | 36 (45.8) | 0.51 | 10 (47.6) | 27 (28.7) | 70 (48.3) | 0.009 | ||||||||
| 7. Renal disease | 16 (35.6) | 41 (31.1) | 28 (33.7) | 0.83 | 8 (38.1) | 29 (30.9) | 48 (33.1) | 0.81 | ||||||||
| 8. Neurological disease | 4 (8.9) | 19 (14.4) | 13 (15.7) | 0.55 | 1 (4.8) | 12 (12.8) | 23 (15.9) | 0.36 | ||||||||
| 9. Haematological disease | 23 (51.1) | 72 (51.5) | 47 (56.6) | 0.73 | 11 (52.4) | 52 (55.3) | 75 (51.7) | 0.86 | ||||||||
| 10. Immunological disease | 34 (75.6) | 90 (68.2) | 64 (77.1) | 0.31 | 12 (57.1) | 66 (70.2) | 106 (73.1) | 0.32 | ||||||||
| 11. ANA | 43 (95.6) | 131 (99.2) | 80 (96.4) | 0.23 | 20 (95.2) | 93 (98.9) | 141 (97.2) | 0.51 | ||||||||