Correlations between Th1 (IFNγ) and Th2 (IL4) cell activity and parameters of disease activity (ESR and serum IgG) in salivary glands (SG) and peripheral blood (PB) in the whole sicca group, the patients with SS and nSS-sicca groups (see also figures 3–5)
| ESR | Serum IgG | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Whole group | nSS | SS | Whole group | nSS | SS | |||||||
| Correlation coefficients with p values (between brackets) when significance was neared or reached—that is, with p values ⩽0.15. Regression lines in cases of significance have been drawn in figs 3, 4, and 5, respectively. | ||||||||||||
| IFNγ (fig 3) | ||||||||||||
| SG | 0.41 | (0.00) | 0.34 | (0.05) | NS | 0.49 | (0.00) | 0.30 | (0.09) | NS | ||
| PB | −0.32 | (0.01) | NS | −0.20 | (0.14) | −0.28 | (0.04) | NS | NS | |||
| IL4 (fig 4) | ||||||||||||
| SG | NS | 0.24 | (0.12) | NS | 0.31 | (0.03) | 0.51 | (0.01) | NS | |||
| PB | NS | NS | NS | −0.25 | (0.07) | −0.31 | (0.08) | NS | ||||
| IFNγ/IL4 (fig 5) | ||||||||||||
| SG | 0.17 | (0.11) | NS | NS | 0.28 | (0.03) | NS | NS | ||||
| PB | −0.38 | (0.00) | NS | −0.33 | (0.04) | −0.32 | (0.01) | 0.38 | (0.04) | −0.24 | (0.11) | |