Carrier frequency of CARD15 variants in patients with Crohn’s disease
| R702W | G908R | 1007fs | Overall* | |
|---|---|---|---|---|
| Numbers of patients carrying R702W, G908R, or 1007fs variants. | ||||
| *Total number of patients in the group carrying at least one variant. The sum of all allelic CARD15 variants is greater than the overall number of patients carrying at least one variant, as some patients carry two different single nucleotide polymorphisms (compound heterozygotes). | ||||
| CARD15+/−, heterozygous for CARD15 gene; CARD15+/+, homozygous for CARD15 gene; SI, sacroiliitis. | ||||
| Crohn’s disease (n = 102) | ||||
| CARD15+/– | 33 | 6 | 21 | 56 |
| CARD15+/+ | 2 | 1 | 0 | |
| Crohn’s disease with no SI (n = 79) | ||||
| CARD15+/– | 21 | 6 | 13 | 38 |
| CARD15+/+ | 2 | 1 | 0 | |
| Crohn’s disease with SI (n = 23) | ||||
| CARD15+/– | 12 | 0 | 8 | 18 |
| CARD15+/+ | 0 | 0 | 0 | |