Demographic data, rheumatoid factor, Larsen score, and immunohistochemical analysis (cells/mm2) at baseline. Data are divided according to radiological progression into two groups: group I (Larsen score <2 points per year of follow up) and group II (Larsen score ⩾2 points/year of follow up)
| Group I (n = 20) | Group II (n = 16) | |
|---|---|---|
| Data represent median (range) unless stated otherwise. | ||
| Sex (M/F) | 14/6 | 1/15 |
| Age, mean (SD) | 66 (13) | 62 (13) |
| Follow up (months) | 47 (22–69) | 66 (34–72) |
| Rheumatoid factor (+/−) | 9/11 | 12/4 |
| Larsen score | 2.0 (0–18) | 1.0 (0–17) |
| Macrophages | ||
| Synovial sublining | 2155 (103–5735) | 2190 (192–6765) |
| Intimal lining layer | 249 (71–671) | 307 (8–1381) |
| Fibroblast-like synoviocytes | 158 (2–1473) | 441 (35–2405) |
| B cells | 53 (0–2854) | 182 (0–3456) |
| Plasma cells | 187 (8–3013) | 410 (1–1212) |
| T cells | 469 (0–1733) | 480 (137–2013) |
| Granzyme B+ cytotoxic cells | 12 (0–63) | 25 (0–346) |