Frequency of antithyroid antibodies and autoimmune thyroiditis in association with primary Sjögren’s syndrome: summary of previous publications and a comparison of their results with our findings
| Country | n | TPO (%) | TG (%) | Both (%) | Total (%) | AIT (%) | Criteria |
|---|---|---|---|---|---|---|---|
| *p<0.05, **p<0.01: results of current study v those of previous studies. | |||||||
| †Controlled studies. | |||||||
| AIT, autoimmune thyroiditis; CS, current study; ECSG, European Community Study Group; NA, not available; TG, thyroglobulin; TPO, thyroid peroxidase. | |||||||
| USA1 | 24 | 10 (42)** | 5 (21) | 5 (21) | 10 (42)** | 13 (54)** | NA |
| Italy2 | 8 | NA | NA | NA | 6 (75)** | 2 (25)* | NA |
| UK3 | 100 | 40 (40)** | NA | NA | 40 (40)** | 14 (14) | Fox’s criteria |
| France4 | 26 | NA | 26 (100)** | NA | 26 (100)** | 8 (31)** | Fox’s criteria |
| Sweden5 | 28 | 10 (36)** | 10 (36)** | 10 (36)** | 10 (36)** | 5 (18)* | Copenhagen18 |
| UK6† | 42 | 14 (33)** | 6 (14) | NA | NA | NA | Fox’s criteria |
| Mexico7 | 33 | 15 (45)** | 6 (18) | NA | 16 (48)** | 11 (33)* | NA |
| UK8 | 74 | 17 (23)* | NA | NA | NA | NA | Fox’s criteria |
| Italy9† | 119 | 21 (18) | 16 (13) | NA | 22 (19) | 16 (13) | ECSG |
| Spain10† | 160 | 25 (16) | 20 (13) | NA | NA | 32 (20)** | ECSG |
| Turkey (CS)† | 53 | 5 (9) | 5 (9) | 4 (8) | 6 (11) | 2 (4) | ECSG |