āA1298C and C677T genotypes and methotrexate related side effects
| A1298C genotype | C677T genotype | |||||||
|---|---|---|---|---|---|---|---|---|
| n | AA | AC | CC* | n | CC | CT | TT | |
| *Number of 1298CC carriers significantly higher among rheumatoid patients with no methotrexate related side effects than among those with side effects (Ļ2 test, pā=ā0.035). | ||||||||
| No with any side effect | 33 | 22 (66.7%) | 8 (24.2%) | 3 (9.1%) | 33 | 15 (45.5%) | 14 (42.4%) | 4 (12.1%) |
| No with no side effects | 60 | 28 (4.07%) | 12 (20.0%) | 20 (33.0%) | 60 | 30 (50.0%) | 24 (40.0%) | 6 (10.0%) |