Frequencies of DMA alleles in patients with or without antiphospholipid antibodies (aPL) in SLE
| Allele | aPL +/− (n = 84/80) | aCL +/− (n = 70/94) | aβ2GPI +/− (n = 50/110) | aPT +/− (n = 32/120) | LA +/− (n = 58/90) | |
|---|---|---|---|---|---|---|
| n = number of alleles in patients with positive aPL v patients with negative aPL among SLE patients. aCL, aβ2GPI, and aPT contain both IgG and IgM class. | ||||||
| †p = 0.035 by 4×2 χ2 test. | ||||||
| ‡p = 0.021 (pc = 0.084) by 2×2 χ2 test. | ||||||
| aβ2GPI, anti-β2GPI antibody; aCL, anticardiolipin antibody; aPT, anti-prothrombin antibody; LA, lupus anticoagulant. | ||||||
| DMA*0101 | 76.2%/88.8% | 75.7%/87.2% | 78.0%/83.6% | 81.3%/82.5% | 75.9%/86.7% | |
| *0102 | 21.4/8.8 | 21.4/10.6 | 20.0/13.6 | 18.8/14.2 | 24.1/8.9‡ | † |
| *0103 | 1.2/2.5 | 1.4/2.1 | 2.0/1.8 | 0.0/2.5 | 0.0/3.3 | |
| *0104 | 1.2/0.0 | 1.4/0.0 | 0.0/0.9 | 0.0/0.8 | 0.0/1.1 | |