Table 3

Risk group genotypes in 322 rheumatoid arthritis patients and 622 affected family based artificial controls

Risk group genotype	Patients (n = 322)		Controls (AFBAC) (n = 622)		OR	95% CI	p Value*
Risk group genotype	n	%	n	%	OR	95% CI	p Value*
*Only statistically significant p values are shown.
†By Fisher’s exact test.
AFBAC, affected family based artificial controls; CI, confidence interval; OR, odds ratio.
S/S	38	11.80	7	1.13	11.76	4.96 to 29.21	<10⁻⁶
S/s	64	19.88	26	4.18	5.69	3.44 to 9.45	<10⁻⁶
N/S	19	5.90	18	2.89	2.10	1.04 to 4.26	0.038
s/s	17	5.28	17	2.73	1.98	0.95 to 4.14
S/P	13	4.04	16	2.57	1.59	0.71 to 3.55
S/p	41	12.73	62	9.97	1.32	0.85 to 2.05
N/s	22	6.83	39	6.27	1.10	0.62 to 1.94
s/p	28	8.70	76	12.22	0.68	0.42 to 1.10
N/p	22	6.83	67	10.77	0.61	0.36 to 1.03
s/P	12	3.73	46	7.40	0.48	0.24 to 0.96	0.037
p/p	20	6.21	79	12.70	0.46	0.26 to 0.78	0.0029
N/N	4	1.24	21	3.38	0.36	0.11 to 1.12	0.037†
p/O	2	0.62	16	25.72	0.24	0.05 to 1.08	0.027
N/P	3	0.93	29	4.66	0.19	0.06 to 0.67	0.0012†
P/p	6	1.86	60	9.65	0.18	0.07 to 0.43	0.000016
P/P	0	0	18	2.89	0.05	0.01 to 0.38	0.00050