Patients in each group (n) | Slow increase in damage | Fast increase in damage | |
---|---|---|---|
*Except when indicated otherwise, values are mean (SD); †p<0.05 Mann-Whitney U test fast increase in damage v slow increase in damage subgroup. | |||
Fast increase in damage is defined as a change in the Larsen score higher than the mean change for the whole group of completers (>4.67); slow increase in damage is defined as a change in Larsen score equal to or lower than the mean change (⩽4.67). | |||
AUC DAS4, area under curve disease activity score four variables; DMARDs, disease modifying antirheumatic drugs; BMD, bone mineral density; IQR, interquartile range. IQR is expressed as a net result of 25th–75th centile. | |||
Baseline Larsen score (0–200), median (IQR) | 166/106 | 20.0 (48.3) | 51.0 (53.5)† |
AUC DAS4 | 166/106 | 20.3 (7.8) | 23.9 (8.0)† |
Use of DMARDs (0–16) | 166/106 | 0.3 (0.4) | 0.4 (0.4)† |
Use of glucocorticoids (0–24), months | 166/106 | 1.9 (6.0) | 3.2 (7.2) |
Change in muscle strength (N), median (IQR) | 156/99 | 8.25 (31.9) | 3.5 (31) |
Change in aerobic fitness (W), median (IQR) | 151/97 | 0.15 (46.10) | −0.1 (39.5)† |
Change in BMD (g/cm2) | 162/104 | −0.015 (0.043) | −0.025 (0.069) |
Attendance rate in exercise sessions (0–100), median (IQR) | 166/106 | 12.2 (77.8) | 0.0 (69.1) |