Clinical data of patients with SSc showing positive anti-PS/PT Ab
| Clinical data | Anti-PS/PT Ab (+) (n = 18) | Anti-PS/PT Ab (−) (n = 94) |
|---|---|---|
| Values are percentages unless otherwise stated. | ||
| mTSS, modified Rodnan total skin thickness score; ESR, erythrocyte sedimentation rate; CRP, C reactive protein. | ||
| *p<0.01 v patients with SSc with negative anti-PS/PT Ab. | ||
| Age at onset (years), mean (SD) | 41 (20) | 46 (15) |
| Sex (male:female) | 4:14 | 9:85 |
| Duration (years), mean (SD) | 5.4 (5.6) | 5.3 (7.0) |
| Skin | ||
| mTSS | 14.7 (12.0) | 10.7 (9.3) |
| Pitting scars | 72* | 32 |
| Digital skin ulcer | 39* | 12 |
| Lung | ||
| Pulmonary fibrosis | 78* | 36 |
| Pulmonary hypertension | 56* | 18 |
| Decreased %VC | 61* | 24 |
| Decreased %Tlco | 89* | 54 |
| Oesophagus | 89 | 63 |
| Heart | 39 | 20 |
| Kidney | 17 | 3 |
| Joint | 44 | 22 |
| Muscle | 11 | 14 |
| Laboratory findings | ||
| Antitopoisomerase I Ab | 56 | 32 |
| Anticentromere Ab | 22 | 39 |
| Anti-RNA polymerase Ab | 11 | 9 |
| Anti-U1RNP Ab | 6 | 7 |
| Raised ESR | 33 | 24 |
| Raised CRP | 22 | 12 |