Genes up regulated more than threefold in early RA
| Category | Gene identifier | Chromosome location | Description |
|---|---|---|---|
| Immune/growth factor | CSTF2 | Xq22.1 | Cleavage stimulation factor |
| CSF3R | 1p34.3–35 | CSF 3 receptor (granulocyte) | |
| TGFBR2 | 3p24.1 | TGFβ receptor II | |
| Metabolism | CYP3A4 | 7q22.1 | Cytochrome P450 subfamily IIIA |
| HSD11B2 | 16q22 | 11β-Hydroxysteroid dehydrogenase 2 | |
| Neuromuscular | SNTA1 | 20q11.2 | Syntropin α, neuromuscular junction protein |
| TNNI2 | 11p15.5 | Troponin I, skeletal, fast twitch | |
| TNNT2 | 1q32 | Troponin T2, cardiac | |
| Transcription | ZNF74 | 22q11.2 | Zinc finger protein 74 (Cos52) |