Distribution of HLA-DRB1 genotypes in patients with severe and benign RA (cohort 2)
| DRB1* | Severe RA (n = 95) | Benign RA (n = 70) | OR (95% CI) | p |
|---|---|---|---|---|
| X is any HLA-DRB1 gene other than HLA-DRB1*04 and 01 alleles. χ2 test was used for analysis. | ||||
| *04/04 | 10 | 5 | 9 (1.1 to 73.7) | 0.014 |
| *04/01 | 11 | 1 | 2 (1.08 to 4.29) | 0.03 |
| *04/X | 37 | 16 | NS | |
| *01/01 | 4 | 1 | NS | |
| *01/X | 20 | 10 | ||
| *X/X | 13 | 37 | 0.14 (0.06 to 0.29) | <0.0001 |