Demographic variables, clinical and laboratory measurements of disease activity, proinflammatory cytokines, and biochemical markers of bone and cartilage turnover in postmenopausal women with rheumatoid arthritis. Values are means (SD) [numbers of patients with available data]
| Characteristics | |
|---|---|
| Age (years) | 57.6 (5.1)) [88] |
| Height (cm) | 162.9 (6.3)) [88] |
| Weight (kg) | 66.5 (12.6)) [88] |
| Body mass index (kg/m2) | 25.0 (4.2)) [88] |
| Disease duration (years) | 15.9 (11.7)) [88] |
| Age at menarche | 13.6 (1.7)) [87) |
| Age at menopause | 49.2 (3.4)) [78] |
| Milk (glasses/day) | 1.8 (1.6)) [88] |
| Cheese (slices/day) | 3.3 (2.5)) [86] |
| Smoking status (%) | [87] |
| Non-smoker | 38 |
| Previous smoker | 30 |
| Current smoker | 32 |
| Disease modifying antirheumatic drugs (%) | 81 [88] |
| Non-steroidal anti-inflammatory drugs (%) | 77 [88] |
| Calcium and vitamin D3 (%) | 6 [88] |
| Previous treatment with glucocorticosteroid >3 months (%) | 43[87] |
| Glucocorticosteroid treatment at present (%) | 22 [88] |
| Cumulative oral prednisolone dose (g) | 2.6 (5.1)) [88] |
| Cumulative injected glucocorticosteroid dose, expressed as prednisolone (g) | 1.1 (1.3)) [88] |
| Low energy peripheral fractures or vertebral fractures (%) | 19 [84] |
| Larsen score (0–5) | 1.36 (1.06) [83] |
| Erosive disease (%) | 89 [83] |
| Risk group according to HLA-DR4 subtyping (1–5) | 3.3 (1.2) [80] |
| Health Assessment Questionnaire (0–3) | 1.0 (0.7) [88] |
| 28 Joint count disease activity score | 5.3 (1.0) [87] |
| Positive serum test for rheumatoid factor (%) | 83 [88] |
| Haemoglobin (g/l) | 129 (12) [88] |
| Erythrocyte sedimentation rate (mm/1st h) | 29 (17) [87] |
| C reactive protein (mg/l) | 17 (17) [87] |
| Tumour necrosis factor α (pg/ml) | 4 (3) [85] |
| Interleukin 1β (pg/ml) | 0.4 (1.2) [87] |
| Interleukin 1 receptor antagonist (pg/ml) | 542 (647) [87] |
| Interleukin 6 (pg/ml) | 23 (32) [87] |
| Interleukin 6 soluble receptor (pg/ml) | 789 (236) [86] |
| Osteoprotegerin (pg/ml) | 112 (97) [83] |
| Carboxyterminal crosslinked telopeptide of type I collagen (ng/ml) | 4.8 (1.9) [77] |
| Carboxyterminal propeptide of type I procollagen (ng/ml) | 133 (41) [78] |
| Insulin-like growth factor-I (ng/ml) | 80 (30) [77] |
| Cartilage oligomeric matrix protein (U/l) | 11 (3) [86] |
| Oestradiol (pmol/l) | 51 (85) [72] |