Epidemiological studies on the risk of cancer in Scl
| All cancers, SIR (95% CI) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Ref | Year | Country | Mean follow up years | No of cases of Scl | All | Male | Female | Sites of risk |
| *CIs not presented; | ||||||||
| †there is some overlap between these two studies. | ||||||||
| 8 | 1982 | Australia | 3.3 | 27 | 6.45 (0.78 to 23.29) | 8.33 (0.21 to 46.28) | 5.26 (0.13 to 29.22) | No significant risk found |
| 9 | 1985 | USA | 4.3 | 262 | 1.81* | 2.46* | 1.58* | Lung |
| 10 | 1993 | Canada | 4.6 | 248 | 7.90* | Lung | ||
| Breast | ||||||||
| 11† | 1993 | Sweden | 5.1 | 233 | 2.4 (1.5 to 3.6) | 1.8* | 2.9* | Lung |
| Non-Hodgkin’s lymphoma | ||||||||
| 12† | 1995 | Sweden | 917 | 1.5 (1.2 to 1.9) | Lung | |||
| Non-melanoma skin cancers | ||||||||
| Primary liver cancer | ||||||||
| Increase in haematopoietic cancers | ||||||||
| 13 | 2000 | Japan | 6 | 43 | 5.1 (1.7 to 10.8) | |||
| 14 | 2000 | USA | 490 | 0.75 (0.45 to 1.18) | 1.14 (0.37 to 2.66) | 0.77 (0.42 to 1.29) | Lung | |
| Breast | ||||||||
| 7 | 2003 | South Australia | 5.5 (male) | 441 | 1.99 (1.46 to 2.65) | Lung | ||
| 6.1 (female) | Diffuse Scl 2.73 (1.31 to 5.02) | |||||||
| Limited Scl 1.85 (1.23 to 2.68) | ||||||||