Proposed EScSG disease activity indices for SSc
| Criteria | Whole series | dcSSc | lcSSc |
|---|---|---|---|
| *To be changed to mRTSS >14. | |||
| TTS, total skin score; Tlco, carbon monoxide transfer factor; ESR, erythrocyte sedimentation rate. | |||
| TTS >20 (Kahaleh’s method)* | 1.0 | ||
| Scleredema | 0.5 | 0.5 | |
| Δ Skin | 2.0 | 3.0 | 2.5 |
| Digital necrosis | 0.5 | ||
| Δ Vascular | 0.5 | 2.0 | 1.0 |
| Arthritis | 0.5 | 1.0 | |
| Δ Articular/muscular | 1.0 | ||
| ↓ Tlco | 0.5 | ||
| Δ Cardiopulmonary | 2.0 | 4.0 | 1.5 |
| ESR >30 mm/1st h | 1.5 | 2.5 | |
| Hypocomplementaemia (C3 and/or C4) | 1.0 | 1.0 | |
| Total maximum disease activity index | 10.0 | 10.0 | 10.0 |