First, second (fourth week), and third (eighth week) measurements of total myalgic score (TMS), Fibromyalgia Impact Questionnaire items (FIQ-5 and FIQ-6), the Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HARS), P300 latency, and amplitudes. Comparisons were performed using Wilcoxon test
| Entry I | 4th Week II | 8th Week III | p I v II | p I v III | |
|---|---|---|---|---|---|
| TMS | 83.5 (9.5) | 84.1 (8.6) | 87.1 (7.6) | NS | <0.05 |
| FIQ-5 pain (VAS) | 7.0 (1.0) | 5.0 (1.7) | 4.3 (1.2) | 0.02 | 0.002 |
| FIQ-6 fatigue (VAS) | 7.3 (1.5) | 5.4 (2.3) | 5.0 (2.4) | 0.02 | 0.005 |
| HARS | 24.2 (7.3) | 16.5 (9.0) | 13.8 (8.6) | 0.02 | 0.002 |
| HDRS | 21.2 (5.2) | 13.9 (6.4) | 11.7 (6.2) | 0.02 | 0.002 |
| P300 latency (ms) | 330.4 (29.9) | 327.3 (33.1) | 335.6 (23.3) | NS | NS |
| N2P3 amplitude (μV) | 11.3 (5.6) | 13.7 (6.3) | 16.7 (5.7) | NS | 0.009 |