HLA alleles associated with severe SLE
| HLA | Patients (%PF) (n=53) | Controls (%PF) (n=110) | OR | p Value | CI |
|---|---|---|---|---|---|
| %PF, percentage phenotype frequency; OR, odds ratio; CI, 95% confidence interval. | |||||
| A1 | 39.60 | 17.80 | 2.99 | <0.001 | 1.06 to 2.08 |
| A2 | 45.30 | 29.70 | 1.95 | <0.001 | 0.52 to 1.02 |
| A19 | 26.50 | 43.40 | 0.48 | <0.001 | 9.62 to 10.72 |
| B15 | 2.00 | 16.30 | 0.16 | <0.001 | 5.07 to 7.23 |
| B27 | 12.20 | 2.30 | 5.40 | <0.001 | 1.42 to 2.54 |
| DRB1* | |||||
| 03 | 50.00 | 6.70 | 9.67 | <0.0001 | 8.41 to 13.56 |
| 14(6) | 12.50 | 40.00 | 0.25 | <0.001 | 1.09 to 2.56 |
| 1001 | 6.30 | 30.00 | 0.21 | <0.001 | 1.84 to 2.34 |
| DQB1* | |||||
| 0302 | 56.30 | 10.00 | 8.02 | <0.0001 | 12.88 to 18.45 |
| 0203 | 12.50 | 50.00 | 0.17 | <0.0001 | 1.32 to 2.56 |