Associations approaching or reaching statistical significance between clinical findings in patients with a T cell response on the SmD183–119 peptide compared with those in patients without T cell response on this autoantigen that was measured by thymidine incorporation. Data were obtained by analysis of 40 clinical findings at any time during the course of disease in all 34 patients with SLE investigated
| Patients (No (%)) | |||
|---|---|---|---|
| Clinical features | With T cell response | Without T cell response | p Values |
| Discoid lupus | 6/10 (60) | 2/22 (9) | 0.041 |
| Sicca syndrome | 9/10 (90) | 10/22 (45) | 0.02 |
| Nephritis | 9/11 (82) | 10/21 (48) | 0.066 |
| Arrhythmia | 3/8 (38) | 1/22 (5) | 0.021 |
| Myocarditis | 6/10 (60) | 2/22 (9) | 0.005 |
| Pericardial effusion | 6/9 (67) | 4/22 (18) | 0.01 |
| Depressions | 5/9 (56) | 1/22 (5) | 0.027 |
| Pleural effusion | 7/9 (78) | 3/20 (15) | 0.001 |
| Pneumonia | 7/9 (78) | 1/20 (5) | < 0.001 |
| Pathol. lung function | 5/8 (63) | 2/19 (11) | 0.011 |
| Lung fibrosis | 5/9 (56) | 1/21 (5) | 0.005 |