Table 1

Detailed data of the patients with primary Sjögren's syndrome with neuropsychiatric symptoms or signs

				Serology
Patient No	Age (years)	Hypoperfusion regions on ^99mTc ECD brain SPECT	Neuropsychiatric symptoms or signs	Anti-Ro (SS-A) antibody	Antiphospholipid antibodies	Antineuronal antibodies
L, left; R, right; Bil, bilateral; F, frontal lobe; P, parietal lobe; T, temporal lobe; O, occipital lobe; B, basal ganglion.
1	28	Negative	Cognition impairment	−	−	−
2	28	Bil P-T-O	Unstable gait	+	+	−
3	29	L F-P-B	Cognition impairment	−	+	+
4	29	Negative	Memory impairment	−	+	+
5	30	Bil P-O	Memory impairment	−	+	+
6	31	Bil P-T-O	Dizziness, headache	+	+	−
7	33	Bil F-P-T	Conscious disturbance	+	−	−
8	33	L F-P-T	Vertigo	−	−	−
9	34	Negative	Frequent syncope	−	+	+
10	34	Bil P-T	Memory impairment	+	+	−
11	35	Negative	Seizure, headache	−	+	−
12	35	Negative	Memory impairment	−	+	−
13	35	Bil P-T	Memory and cognition impairment	−	−	−
14	36	Negative	Memory impairment	−	−	+
15	36	R P-T	Cognition and memory impairment	−	+	+
16	37	R F-P-T	Memory and cognition impairment	−	+	−
17	38	R P-O	Drowsiness, depression	−	−	−
18	39	Negative	Cognition impairment	−	−	+
19	40	Negative	Seizure, syncope	−		−
20	40	L F-P-T	Memory impairment	−	+	+
21	41	R F-P-T	Cognition impairment	+	−	+
22	42	Negative	Seizure, memory, and cognition impairment	−	−	+
23	43	L P-T-B	Depression		+	−
24	43	Negative	Memory impairment	−	−	−
25	43	Lt P-T-B	Drowsiness, depression	−	+	+
26	44	R F-P	Insomnia, depression	−	−	−
27	45	Bil F-P-T-B	Mental retardation, memory impairment	+	+	+
28	45	Negative	Cognition impairment	−	−	+
29	46	Negative	Cognition impairment	−	−
30	48	Negative	Conscious disturbance	−	+	+
31	49	R F-P-B	Insomnia, dizziness	+	+
32	50	Negative	Memory impairment	−	−