Effect of HLA-B27, HLA-DR1, and HLA-B15 on disease activity and functioning indices
| HLA-B27 | HLA-DR1 | HLA-B15 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Positive | Negative | p | Positive | Negative | p | Positive | Negative | p | |
| BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index. | |||||||||
| *Continuous variable, Student's t test. | |||||||||
| NS, not significant. | |||||||||
| This analysis was made in 168 patients. | |||||||||
| Number (%) | 113 (67) | 55 (33) | 48 (28) | 121 (72) | 38 (23) | 130 (77) | |||
| BASDAI, mean (SD) | 4.7 (2.2) | 3.6 (2.4) | 0.006* | 4.3 (2.4) | 4.4 (2.4) | NS | 4.5 (2.3) | 4.3 (2.4) | NS |
| BASFI, mean (SD) | 4.3 (2.7) | 3.1 (2.3) | 0.004* | 3.9 (2.8) | 3.9 (2.5) | NS | 3.8 (2.5) | 3.4 (2.6) | NS |
| Schober's test (cm), mean (SD) | 4.0 (1.8) | 4.6 (1.2) | 0.02* | 4.5 (1.6) | 4.1 (1.7) | NS | 4.5 (1.4) | 4.1 (1.7) | NS |
| Chest expansion (cm), mean (SD) | 3.6 (1.4) | 4.1 (1.4) | 0.03* | 3.8 (1.4) | 3.8 (1.4) | NS | 3.86 (1.3) | 3.8 (1.5) | NS |