Clinical features at five years by reasons for work disability
| Reasons for PWD | |||||||
|---|---|---|---|---|---|---|---|
| Total No (%) | Working No (%) | RA No (%) | RA+other No (%) | RA+comorbidity No (%) | Not RA No (%) | OR (95% CI) | |
| Patients not included: missing job status at five years (n=7); started work after baseline visit (n=8); missing DAS at five years (n=21). | |||||||
| Total | 346 (100) | 211 (61) | 80 (23) | 8 (2) | 16 (5) | 31 (9) | |
| Sex | |||||||
| Male | 140 (40) | 85 (40) | 34 (43) | 3 (38) | 6 (38) | 12 (39) | |
| Female | 206 (60) | 126 (60) | 46 (58) | 5 (63) | 10 (63) | 19 (61) | |
| Job at baseline | |||||||
| Manual | 79 (23) | 42 (20) | 28 (35) | 2 (25) | 3 (19) | 4 (13) | |
| Semi-manual | 60 (17) | 33 (16) | 17 (21) | 1 (13) | 5 (31) | 4 (13) | |
| Semi-sedentary | 80 (23) | 51 (24) | 19 (24) | 0 | 0 | 10 (32) | Manual v sedentary |
| Sedentary | 127 (37) | 85 (40) | 16 (20) | 5 (63) | 8 (50) | 13 (42) | 2.3 (1.4 to 3.8) |
| Carstairs deprivation | |||||||
| 1 (least) | 83 (24) | 59 (29) | 11 (14) | 1 (13) | 5 (31) | 7 (23) | |
| 2 | 87 (26) | 56 (27) | 16 (21) | 4 (50) | 2 (13) | 9 (30) | |
| 3 | 77 (23) | 43 (21) | 23 (29) | 1 (13) | 5 (31) | 5 (17) | |
| 4 | 56 (17) | 35 (17) | 11 (14) | 0 | 3 (19) | 7 (23) | 1, 2, 3 v 4, 5 |
| 5 (worst) | 36 (11) | 14 (6.8) | 17 (22) | 2 (25) | 1 (6.3) | 2 (6.7) | 2.3 (1.4 to 3.8) |
| RF | |||||||
| Neg | 72 (21) | 42 (20) | 18 (23) | 1 (13) | 2 (13) | 9 (29) | |
| Pos | 274 (79) | 169 (80) | 62 (78) | 7 (88) | 14 (88) | 22 (71) | |
| Erosions on x ray examination | |||||||
| Absent | 70 (20) | 52 (25) | 7 (8.8) | 0 | 2 (13) | 9 (29) | |
| Present | 276 (80) | 159 (75) | 73 (91) | 8 (100) | 14 (88) | 22 (71) | 2.8 (1.4 to 5.8) |
| Nodules | |||||||
| Absent | 239 (69) | 155 (73) | 50 (63) | 6 (75) | 8 (50) | 20 (65) | |
| Present | 107 (31) | 56 (27) | 30 (38) | 2 (25) | 8 (50) | 11 (35) | 1.8 (1.1 to 3.0) |
| Functional grades | |||||||
| I | 173 (50) | 131 (62) | 17 (21) | 2 (25) | 3 (20) | 20 (65) | |
| II | 153 (44) | 74 (35) | 53 (66) | 6 (75) | 10 (67) | 10 (32) | I v II–IV |
| III/IV | 19 (5.5) | 6 (2.8) | 10 (13) | 0 | 2 (13) | 1 (3.2) | 5.9 (3.3 to 10) |
| Drugs 5 years | |||||||
| 0 NSAIDs | 51 (15) | 35 (17) | 7 (8.8) | 1 (13) | 1 (6.3) | 7 (23) | |
| 1 DMARD ×1 | 149 (43) | 97 (46) | 26 (33) | 5 (63) | 7 (44) | 14 (45) | |
| 2 DMARD ×2 | 72 (21) | 44 (21) | 19 (24) | 1 (13) | 3 (19) | 5 (16) | 0, 1 v 2, 3 |
| 3 DMARD ×3 | 74 (21) | 35 (17) | 28 (35) | 1 (13) | 5 (31) | 5 (16) | 2.1 (1.3 to 3.4) |
| DAS 5 years | |||||||
| 1 Remission | 46 (13) | 35 (17) | 3 (3.8) | 1 (13) | 1 (6.3) | 6 (19) | |
| 2 Partial | 55 (16) | 41 (19) | 7 (8.8) | 2 (25) | 0 | 5 (16) | 1, 2 v 3 |
| 3 Active RA | 224 (65) | 127 (60) | 61 (76) | 5 (63) | 13 (81) | 18 (58) | 4.2 (2.1 to 8.4) |