Diagnostic sensitivities (0.05 confidence intervals) of antifilaggrin autoantibodies detected by indirect immunofluorescence on rat oesophagus epithelium (“AKA”), by immunoblotting on human epidermis filaggrin (AhFA-IB) and by ELISA (AhFA-ELISA-pur or AhFA-ELISA-rec)
| Specificity ⩾95% | Specificity ⩾99% | |
| “AKA” | 0.51 (0.45 to 0.58) | 0.40 (0.34 to 0.46) |
| AhFA-IB | 0.59 (0.53 to 0.66) | 0.37 (0.30 to 0.43) |
| AhFA-ELISA-pur | 0.48 (0.41 to 0.54) | 0.22 (0.17 to 0.27) |
| AhFA-ELISA-rec | 0.52 (0.46 to 0.59) | 0.31 (0.25 to 0.37) |