Table 2

Cytokine profile of CD3+ peripheral blood T lymphocytes in healthy controls (HC), patients with spondyloarthropathy (SpA) at baseline, and patients with rheumatoid arthritis (RA)

HC (n=15) SpA (n=20) RA (n=19)
IFNγ
 % positive cells33.0  (13.1–53.9)2-150 2-151 20.9  (9.5–65.1)2-150 19.9  (8.4–53.4)2-151
 MFI153.0 (77.0–216.7)2-150 110.0 (61.5–192.1)2-150 2-152 164.4 (53.1–343.7)2-152
IL2
 % positive cells25.7 (13.4–39.6)2-150 17.5 (7.5–35.4)2-150 2-152 31.2 (13.1–56.7)2-152
 MFI104.6 (67.2–150.2)2-150 80.5 (53.4–139.2)2-150 2-152 131.6 (63.3–237.2)2-152
IL4
 % positive cells1.8 (0.4–3.6)2-151 1.5 (0.3–8.7)1.0 (0.3–2.7)2-151
 MFI68.5 (33.5–304.6)67.5 (31.1–488.7)49.9 (33.4–164.9)
IL10
 % positive cells1.1 (0.2–5.6)2-150 2-151 3.8 (0.9–15.4)2-150 5.4 (1.8–37.5)2-151
 MFI24.8 (12.4–69.4)29.4 (12.8–78.0)31.5 (17.5–70.4)

  • Results are expressed as median (range).

  • Percentage of positive T cells and mean fluorescence intensity (MFI) were assessed by flow cytometry for interferon (IFN)γ, interleukin (IL)2, IL4, and IL10.

  • ↵2-150 p⩽0.05 HC v SpA;

  • ↵2-151 p⩽0.05 HCv RA;

  • ↵2-152 p⩽0.05 SpAv RA.