Table 1

Serum TIMP-1, TIMP-2, and MMP-1 levels in patients with diffuese cutaneous systemic sclerosis (dcSSc), limited cutaneous SSc (lcSSc), Raynaud's phenomenon (RP), and in normal controls

dcSSc lcSSc RP Normal
TIMP-1 (ng/ml)
 Median403.5353.8305.3275.0
 (Interquartile range, 25th–75th)(314.0–517.1)(312.4–469.2)(259.4–396.4)(229.5–348.0)
 Number83878098
TIMP-2 (ng/ml)
 Median187.0177.0141.5165.5
 (Interquartile range, 25th–75th)(145.0–208.0)(138.0–193.0)(113.5–178.5)(141.5–190.5)
 Number83878092
MMP-11-150 (ng/ml)
 Median3.5303.9102.3902.380
 (Interquartile range, 25th–75th)(1.455–7.275)(1.505–7.060)(1.000–4.010)(1.640–3.780)
 Number82877797
  • 1-150 MMP-1 assay results shown were analysed after assigning a minimum assay result of 1 ng/ml.