Table 1

Results of laboratory tests on three patients with severe systemic atherosclerosis

Laboratory parameter Patient 1 Patient 2 Patient 3 Normal values
Thrombocyte count (× 109/l)214179336150–350
Anticardiolipin antibodies
 IgM+++−ve
 IgG++++++++−ve
Lupus anticoagulant−ve−ve−ve−ve
Wassermann test−ve−ve−ve−ve
aPTT (seconds)38352920–40
Fibrinogen (g/l)6.05.83.82.0–4.0
Creatinine (μmol/l)1348517755–110
Triglycerides (mmol/l)3.22.11.50.5–2.0
Cholesterol (mmol/l)4.26.83.94.0–6.5
HDL cholesterol (mmol/l)0.71.01.0>1.0
LDL cholesterol (mmol/l)2.13.72.31.68–4.53
Vitamins (before treatment)
 Vitamin B6 (nmol/l)95NDND35–105
 Vitamin B12 (nmol/l)0.180.190.460.13–0.60
 Folate (nmol/l)4.14.19.95.0–30.0
Methionine loading (I) (μmol/l)
 Homocysteine (pre/post)103/15942/7827/94<15/<50
Methionine loading (II) (after folate treatment)
 Homocysteine (pre/post)13/528.6/28.618/52
  • aPTT = activated partial thrombin time; HDL = high density lipoprotein; LDL = low density lipoprotein; ND = not determined.