Main characteristics of four patients with chronic hepatitis C virus infection and peripheral neuropathy without mixed cryoglobulinaemia
| Characteristic | Patient No 1 | Patient No 2 | Patient No 3 | Patient No 4 |
| Age/sex | 78/M | 40/M | 62/F | 46/M |
| Mode of infection | ? | Intravenous drug user | ? | ? |
| HCV infection | ||||
| Diagnosis | 1991 | 1997 | 1997 | 1997 |
| PCR1-150 | + | + | + | + |
| Liver biopsy | Knodell 9, Metavir A3F3 | Knodell 4, Metavir A0F0 | Knodell 6, Metavir A1F1 | Knodell 5, Metavir A1F1 |
| Genotype | 2 | 4 | 1b | 1b |
| Extrahepatic manifestations | Sicca syndrome | Arthralgia, myalgia, Raynaud's phenomenon | Arthralgia | Arthralgia |
| Cryoglobulinaemia (No of determinations) | 11 (1991–1999) | 6 (1997–1999) | 4 (1998–2000) | 8 (1998–2000) |
| Rheumatoid factor | − | − | − | − |
| C4 level | Normal | Normal | Normal | Normal |
↵1-150 PCR = HCV viraemia by polymerase chain reaction.