Phenotypic analysis of isolated intraepithelial lymphocytes (IELs) and lamina propria lymphocytes (LPLs) from colonic and ileal biopsy specimens
| Colon | Ileum | ||||||
|---|---|---|---|---|---|---|---|
| IELs | LPLs | IELs | LPLs | ||||
| CD4 | 32 (20–48) | 62 (51–74) | 22 (11–33) | 64 (47–66) | |||
| CD8 | 54 (35–71) | 32 (20–50) | 72 (51–85) | 36 (26–52) | |||
| CD4/CD8 | 0.6 (0.3–1) | 2.1 (1–3.4) | 0.3 (0.2–0.7) | 1.8 (0.9–2.2) | |||
| αEβ7 | 64 (31–82) | 19 (5–34) | 87 (64–95) | 33 (23–45) | |||
| α4β7 | 1.4 (0.4–2.4) | 17 (9–40) | 0.3 (0.3–1.8) | 27 (21–49) | |||
Cell membrane marker expression was analysed in isolated colon and ileum lymphocytes in seven patients (two normal controls and five patients with spondyloarthropathy). Results are expressed as the median (range) percentage of CD3+ cells positive for the different markers.