Whole series p | dSSc p | lSSc p | |
Generalised complaints | 0.0019 | 0.0100 | |
Δ-Gen | 0.0030 | 0.0013 | |
Scleredema | 0.0041 | 0.0015 | |
Melanoderma | 0.0002 | 0.0018 | |
TSS*>20 | 0.0001 | 0.0035 | |
Δ-Skin | 0.0001 | 0.0001 | 0.0001 |
Digital necrosis | 0.0001 | 0.0001 | |
Δ-Vasc | 0.0001 | 0.0001 | 0.0001 |
Dyspnoea | 0.0001 | 0.0084 | 0.0046 |
↓ FVC* | 0.0001 | 0.0251 | 0.0032 |
↓ Tlco * | 0.0001 | 0.0087 | 0.0020 |
Δ-HL* | 0.0001 | 0.0001 | 0.0001 |
Arthritis | 0.0001 | 0.0432 | 0.0154 |
Muscle involvement | 0.0007 | 0.0316 | 0.0227 |
Δ-JM* | 0.0001 | 0.0001 | 0.0001 |
Tendon rubs | 0.0089 | ||
ESR* >30 mm/1st h | 0.0001 | 0.0209 | 0.0001 |
↑ CRP* | 0.0070 | ||
↑ LDH* | 0.0033 | 0.0414 | 0.0472 |
↑ CK* | 0.0420 | 0.0270 | |
Hypocomplementaemia3-151 | 0.0124 | 0.0487 |
TSS = total skin score; FVC = forced vital capacity <80% of predicted value; Tlco = carbon monoxide transfer factor <80% of the predicted value; Δ-HL = cardiopulmonary; Δ-JM = articular/muscular; ESR = erythrocyte sedimentation rate; CRP = C reactive protein; CK = creatine kinase; LDH = lactic dehydrogenase.
↵3-151 Reduced C3 or C4 complement levels.