Table 5

Risk factors of drug induced persistent proteinuria (PP). Data are given as mean (SD) or number (%)

	Patients with drug induced PP (n=14)	Patients without proteinuria (n=212)	p Value
At entry
CRP^5-151 (mg/l)	53.4 (50.0)	17.7 (24.5)	<0.001^5-150
ESR^5-151 (mm/1st h)	60.2 (22.0)	43.1 (24.6)	<0.05^5-150
RF^5-150 positive (No (%))	11 (79)	179 (84)	NS^5-151
Sex (F/M)	12/2	164/48	NS
Age ⩾50 (No (%))	11 (79)	111 (52)	<0.05
Haematuria at the entry (No (%))	4 (29)	35 (17)	NS

During observation period
No of DMARDs^5-151 used	2.57 (1.16)	2.07 (1.50)	NS
No of gold and SH^5-151 compounds used	1.50 (0.65)	1.32 (0.90)	NS
Persistent haematuria (No (%))	8 (57)	30 (14)	<0.0005

↵5-150 Mann-Whitney U test.
↵5-151 CRP = C reactive protein; ESR = erythrocyte sedimentation rate; RF = rheumatoid factor; DMARDs = disease modifying antirheumatic drugs; SH = sulphydryl; NS = not significant.