Characteristics of patients with rheumatoid arthritis (RA) using non-steroidal anti-inflammatory drugs (NSAIDs), who returned all three questionaires within one year. Comparison between high risk and low risk patients with RA. Results are shown as No (%)
| Patients with RA, NSAID users | |||||||
|---|---|---|---|---|---|---|---|
| Low risk (n=515) | High risk (n=731) | Total 1246 (100%) | Odds ratio (95% confidence interval) | ||||
| Age <60 years | Age ⩾60 years | ||||||
| Ulcer in medical history, No (%) | Absent (A) 506 (41) | Present (B) 48 (4) | Absent (C) 570 (46) | Present (D) 108 (9) | |||
| or 9 unknown | or 5 unkown | ||||||
| Events | 1 (0.2) | 0 | 10 (1.8) | 5 (5) | 16 (1.3) | 10.8 (1.42 to 81.8) | |
| Ulcers | 1 (0.2) | 0 | 5 (0.9) | 2 (2) | 8 (0.6) | 4.97 (0.61 to 40.5) | |
| Complications | 0 (0) | 0 | 5 (0.9) | 3 (3) | 8 (0.6) | p<0.05 | |
| Gastroprotection | 149 (29) | 26 (54) | 249 (44) | 79 (73) | 5081-151 (41) | 1.66 (1.42 to 1.93) | |
| GI complaints1-150 | |||||||
| Epigastric pain | 61 (12) | 11 (23) | 47 (9) | 17 (16) | 0.85 (0.60 to 1.22) | ||
| Heartburn | 62 (12) | 7 (15) | 47 (9) | 22 (20) | 0.82 (0.58 to 1.18) | ||
| Nausea | 52 (10) | 6 (13) | 31 (6) | 9 (8) | 0.60 (0.40 to 0.90) | ||
| Vomiting | 14 (3) | 3 (6) | 11 (2) | 5 (5) | 0.96 (0.47 to 1.92) | ||
| Belching | 60 (12) | 11 (23) | 56 (10) | 18 (17) | 1.00 (0.70 to 1.42) | ||
| Puffy feeling in the stomach | 66 (13) | 16 (33) | 52 (9) | 14 (13) | 0.86 (0.61 to 1.21) | ||
| Current treatment | |||||||
| DMARDs1-150 | 424 (84) | 38 (79) | 408 (72) | 67 (62) | 944 (76) | 0.62 (0.47 to 0.82) | |
| Corticosteroids | 74 (15) | 9 (19) | 111 (20) | 25 (23) | 219 (18) | 1.47 (1.09 to 2.00) | |
| Anticoagulants | 8 (2) | 0 | 14 (3) | 6 (6) | 28 (2) | 1.78 (0.78 to 3.92) | |
| Cardiovascular drugs | 66 (13) | 10 (21) | 149 (26) | 37 (34) | 263 (21) | 2.49 (1.84 to 3.38) | |