Placebo (n=121) | IL1Ra | ||||
---|---|---|---|---|---|
30 mg (n=119) | 75 mg (n=116) | 150 mg (n=116) | |||
Mean age (y) | 52 | 53 | 53 | 54 | |
Mean duration of RA (y) | 3.7 | 4.3 | 4.2 | 3.9 | |
Rheumatoid factor (% positive) | 69 | 71 | 69 | 69 | |
Erosions (% positive) | 74 | 77 | 74 | 69 | |
Previous DMARD use (%) | 81 | 79 | 75 | 66 | |
Corticosteroid use (%) | 41 | 49 | 41 | 41 | |
NSAID use (%) | 89 | 82 | 88 | 85 |
DMARD, disease modifying antirheumatic drug; NSAID, non-steroidal anti-inflammatory drug.