Immunostaining of cytokines in early synovial biopsy specimens of RA patients
|  Cytokine | RA patients | Positive staining (%) |
|---|---|---|
| TNF | n=28 | 50 |
| IL1b | n=28 | 100 |
| IL17 | n=28 | 70 |
Five blind synovial needle biopy specimens per RA patient were taken and three sections of at least three suitable (sufficient cellularity) biopsy specimens were evaluated. Staining is considered negative when mean values were not significantly different from control staining with irrelevant antibodies.