Table 1

Evolution of cryoglobulinaemia, rheumatoid factor, and complement levels

Date Cryoglobulinaemia (μg/ml)1-150 Type Rheumatoid factor (Rose-Waaler test) C4 (g/l) CH50 (%)1-152
January 1994  29Oligoclonal IgM0<0.06
40
June 1996  25Oligoclonal IgM1 / 128<0.06
25
August 1996  17Oligoclonal IgMND<0.06
<20
December 1996 188III, polyclonal IgG, IgA, and IgMND<0.07
<20
March 1997   41 / 1280.10
50
October 1998  63III, polyclonal IgG, IgA, and IgMNDND
November 199811051-151 II, IgMκ + polyclonal IgG, IgA, and IgMNDND
December 199816631-151 II, IgMκ + polyclonal IgG, IgA, and IgMNDND
January 199916601-151 II, IgMκ + polyclonal IgG, IgA, and IgMNDND
February 199910311-151 II, IgMκ + polyclonal IgG, IgA, and IgM1/1280.08
60
March 199910001-151 II, IgMκ + polyclonal IgG, IgA, and IgM1/128ND
April 1999 2731-151 (after plasmapheresis)II, IgMκ + polyclonal IgG, IgA, and IgM1/1280.09
30
May 1999 8481-151 II, IgMκ + polyclonal IgG, IgA, and IgMNDND

  • ↵1-150 Normal <15 μg/ml.

  • ↵1-151 Determination performed using the method described above since November 1998.

  • ↵1-152 Normal range 60–120%.