Table 5

Comparisons of demographic, disease variables, and health status measures between patients with SLE with and without at least one sicca symptom and sSS. Mean (SD) for continuous, number (%) for categorical variables

Sicca symptomsSecondary Sjögren's syndrome
Present (n=49)Absent (n=32)Present (n=9)Absent (n=72)
Demographics
 Female sex44  (90)28  (88)9  (100)63  (88)
 Age44.8 (12.7)44.1 (12.4)48.6 (11.1)44.0 (12.6)
 Smokers (current)17 (35)9 (29)4 (44)22 (31)
 Xerogenic drugs14 (29)5-150 3 (9)3 (33)14 (19)
Disease variables
 Age at disease onset34.6 (13.4)36.8 (12.7)37.5 (11.8)35.2 (13.3)
 Disease duration8.3 (5.5)7.0 (4.7)8.0 (5.1)7.2 (5.3)
 Disease activity (SLEDAI)6.67 (5.5)6.68 (5.9)6.67 (6.0)6.68 (5.6)
 Organ damage (SLICC/ACR-DI)2.42 (2.4)5-150 1.13 (1.5)1.89 (3.8)1.91 (1.9)
 Number of ARA/ACR criteria5.49 (1.4)5.53 (1.2)5.4 (0.9)5.5 (1.4)
 ESR (mm/1st h)26.5 (20.3)22.1 (20.9)26.1 (11.2)24.6 (20.4)
 Anti-dsDNA antibody29 (59)18 (56)4 (44)43 (60)
 Anti-SSA antibody16 (33)16 (50)8 (89)5-150 26 (36)
 Anti-SSB antibody8 (16)5 (16)5 (56)5-150 8 (11)
 C3 decreased (<0.67 g/l)4 (8)4 (13)1 (11)7 (10)
 C4 decreased(<0.13 g/l)18 (37)11 (34)5 (56)24 (33)
 Renal disorder8 (16)6 (19) 05-150 14 (19)
Health status measures
 SF-36 physical61.6 (27.1)5-150 75.8 (21.9)58.9 (33.7)68.2 (24.9)
 SF-36 bodily pain47.1 (23.8)5-150 58.9 (27.6)51.3 (31.7)51.8 (25.3)
 SF-36 vitality33.2 (22.2)5-150 46.5 (21.0)25.6 (18.8)5-150 40.1 (22.5)
 SF-36 general health40.3 (25.5)5-150 53.5 (27.8)39.9 (25.3)46.2 (27.3)
 SF-36 mental69.8 (17.9)73.0 (16.0)76.0 (12.9)70.5 (17.6)
 SF-36 social64.5 (23.4)5-150 75.4 (24.1)61.1 (20.2)69.8 (24.5)
 MHAQ1.44 (0.49)5-150 1.12 (0.24)1.44 (0.53)1.30 (0.43)
 VAS pain37.7 (21.3)5-150 26.3 (23.9)31.9 (25.6)33.4 (22.8)
 VAS fatigue60.6 (26.3)5-150 38.9 (30.3)68.7 (23.1)5-150 48.6 (29.9)
 Patient global assessment2.73 (0.91)2.44 (1.01)2.78 (0.83)2.60 (0.97)
  • Two sample t test for continuous and χ2 for categorical variables.

  • 5-150 p<0.05.