Follow up neuropsychiatric and PET findings in 13 patients with and one patient without initial symptoms (patient 28)
| Patient no | Diagnosis | SLEDAI4-150score | Time period after initial PET (months) | CNS symptoms | Treatment | Follow up PET findings | ||||||
| 1 | SLE | 2 | 10 | complete regression (depression, headache, memory impairment) | intensified: S, bC (n=7) | parieto-occipital and nucleus caudatus normalised, occipito-frontal unchanged | ||||||
| 2 | SLE | 0 | 4 | improved (impairment of concentration and memory) | first introduced: S, oC | parieto-occipital B normalised | ||||||
| unchanged (amaurosis fugax attacks, oscillopsia) | parietal R improved | |||||||||||
| 0 | 9 | worsened (impairment of concentration) | unchanged to month 4 | parieto-occipital B and parietal R worsened again | ||||||||
| 3 | SLE | 5 | 2 | improved (psychomotorous unrest, obsessive-compulsive neurosis) | intensified: S, bC (n=3) | parietal B and frontal B normalised, parietal R unchanged | ||||||
| 4 | SLE | 8 | 13 | improved (stroke) | reduced: S | parietal R, parieto-occipital R, basal ganglia R and temporal R worsened | ||||||
| worsened (headache, impairment of concentration and memory) | ||||||||||||
| 5 | SLE | 9 | 30 | improved (depression) | reduced: S,A | unchanged | ||||||
| unchanged (vertigo, gait disturbance, headache) | ||||||||||||
| 6 | SLE | 1 | 3 | complete regression (vertigo, headache) | intensified: S,A | unchanged | ||||||
| unchanged (relapsing diplopia) | ||||||||||||
| 7 | SLE | 16 | 33 | complete regression (headache, depression, paraesthesia) | unchanged: S | unchanged | ||||||
| unchanged (impairment of memory) | ||||||||||||
| 13 | SLE | 18 | 10 | improved (headache) | intensified: S, bC (n=6) | normalised | ||||||
| 14 | SLE | 4 | 5 | improved (headache) | first introduced: S,CyA | normalised | ||||||
| 15 | SLE | 7 | 5 | improved (impairment of concentration) | intensified: S, bC (n=6) | normalised | ||||||
| complete regression (headache) | ||||||||||||
| 16 | SLE | 4 | 9 | complete regression (reactive depression, anxiety, vertigo) | changed from S,oC to S, bC (n=6) | normalised | ||||||
| 17 | SLE | 0 | 5 | improved (impairment of concentration) | Reduced: S | parieto-occipital B slightly improved | ||||||
| 18 | SLE | 4 | 24 | complete regression (memory impairment) | Unchanged: S, A | parieto-occipital R unchanged | ||||||
| parieto-occipital L normalised | ||||||||||||
| 28 | SLE | 2 | 13 | none | Reduced: S | unchanged (normal) | ||||||
↵4-150 SLEDAI score (maximum possible score: 105). Abbreviations as in table 2.