Dissociation constants (KD) of TNFα binding to various sTNF-RIs
| Receptor type | KD (pM) |
| PEG sTNF-RI | 557 |
| E coli derived 4.0 domain sTNF-RI | 794 |
| CHO cell derived 4.0 domain sTNF-RI | 338 |
| r-HuTNFbp PEGylated Dimer | 240 |
The binding of TNFα to various sTNF-RI was measured by the BIAcore chips coated with each of the sTNF-RI forms. KDvalues were determined from Scatchard analysis of the binding data.