Table 4

Global and peripheral assessments before and at days 14, 42, and 84 after treatment

Baseline Day 14 Day 42 Day 84
Global assessments (n=21)
Patient global (0–100)57 (27–100)23 (3–52)4-160 11 (1–45)4-160 10 (1–73)4-160
Patient pain (0–100)70 (23–100)25 (4–61)4-160 13 (1–50)4-160 10 (1–86)4-160
Doctor global (0–100)57 (12–79)23 (5–36)4-160 11 (1–45)4-160 10 (5–75)4-160
ESR4-151 (mm/1st h)44 (10–101)6 (2–30)4-160 5 (2–38)4-160 4 (2–68)4-160
CRP4-151 (g/l)0.046 (0.007–0.29)0.003 (0–0.01)4-160 0.002 (0–0.017)4-160 0.006 (0–0.155)4-160
Peripheral assessments (n=18)
Morning stiffness (minutes)90 (10–300)5 (0–150)4-160 10 (0–150)4-150 5 (0–60)4-160
Pain peripheral joints (0–100)75 (20–99)27 (1–49)4-160 10,5 (0–31)4-160 12 (0–84)4-160
Tender joint count (0–68)6 (1–18)2 (0–11)4-160 0 (0–7)4-160 0 (0–5)4-160
Swollen joint count (0–66)3.5 (1–12)1 (0–9)4-160 0 (0–7)4-160 0 (0–7)4-160
  • Values are given as medians (range).

  • 4-150 p⩽0.01;

  • 4-160 p⩽0.001 (determined by Wilcoxon signed ranks test compared with baseline).

  • 4-151 ESR = erythrocyte sedimentation rate; CRP = C reactive protein.